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Historically, the heart has been considered a vital organ due to its function as an impeller and aspirating blood pump, allowing the fi siological perfusion to every corner of the human body. However, behind this pump role lies a little-discussed function, that is, the endocrine-metabolic role of the heart, as a hormone synthesizing organ and, because of its pump function, a distributor of hormones foreign to it. Understanding the incidence of peptides synthesized in the heart offers a new perspective on the relevance of the heart in homeostasis and how cardiovascular disease can alter metabolism. The present work aims to review the most current information on the role of natriuretic peptides produced in the heart and their endocrine-metabolic function. These are atrial, brain and C-type natriuretic peptides. It is concluded that the conception of the heart as an organ of endocrine-metabolic regulation, whose hormones are essential for the homeostasis of the organism, is fundamental for the medicine of this century and for future advances in new therapeutic strategies to improve the quality of life of patients.
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Copyright (c) 2021 Chenhua Xu, Sichao Ye, Qingli Qiao
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Prof. Prakash Deedwania
University of California,
San Francisco, United States
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News & Announcements
2024-09-08
September 16: International Day of Interventional Cardiology
WInternational Interventional Cardiology Day aims to raise public awareness of cardiovascular disease and surgery, related complications, and prevention and care.
2024-06-21
Welcome Our New Editorial Board Members
We are delighted to welcome these experts to our Editorial Board for Cardiac and Cardiovascular Research.
Section Collections
Deadline: 2024-10-17
Pediatric Cardiology and Congenital Heart Disease
Guest Editor: Dr. Apollos Daniel
Keywords: Cardiac; Cardiovascular care; Cardiac therapeutic...